Platelet-rich fibrin I-PRF

Platelet-rich fibrin is a new-generation platelet concentrate that is obtained from the patient's blood by collecting it and then centrifuging it. The material is rich in stem cells and growth factor-producing platelets. Fibrin differs from platelet-rich plasma in that it has a cross-linked, three-dimensional structure, thanks to which it creates a mesh at the injection site that supports the skin and stimulates the subcutaneous tissue to renew, giving the effect of gentle filling (volumetry), and the platelets contained in it for a long time are stimulated to secreting growth factors rebuilding the skin structure.

The effect of platelet-rich fibrin on tissues is based on two basic mechanisms:

First of all, thanks to the content of a large amount of growth factors, it stimulates various types of regenerative processes in tissues. As a result, there are a number of benefits in terms of improving the firmness, vitality and health of tissues (e.g. skin).
The second mechanism is the action of platelets, i.e. thrombocytes, which, apart from their obvious function of ensuring proper blood clotting, also secrete significant amounts of growth factors, which additionally support the activity of those factors that are already present.
Platelet-rich fibrin is used for comprehensive biostimulation and skin rejuvenation. The treatment regenerates collagen and elastin fibers responsible for keeping the skin in good condition, making it an excellent method of rejuvenating and improving the appearance of the face. It improves the firmness and elasticity of the skin, thickens it, removes wrinkles and nasolabial folds, definitely rejuvenates the face oval and the eye area. It also works to improve the appearance of more delicate and difficult areas such as the neck, cleavage or hands. It is also very effective in treating baldness or removing scars, especially hypertrophic ones, as well as removing stretch marks.

The preparation is natural, safe and does not cause allergic reactions.

Natural stimulation of hair growth and scalp rejuvenation

Treatment using I-PRF, a platelet-rich fibrin, is an innovative autologous regenerative therapy that effectively stimulates hair growth, improves scalp condition, and supports combating hair loss. With a high concentration of platelets, stem cells, and growth factors, I-PRF acts directly at the site of the problem – stimulating hair follicles, improving microcirculation, and accelerating regenerative processes within the scalp.

It is an excellent alternative for individuals who want to halt hair loss and thicken their hair in a completely natural way without burdening the body with synthetic substances.

How does I-PRF work on the scalp?

During the procedure, platelet-rich fibrin is isolated from the patient's blood – a substance with a gel-like consistency containing:

• Concentrated platelets
• CD34+ stem cells
• Growth factors (PDGF, VEGF, TGF-β)

Injected into the scalp, I-PRF works on three levels:

• Stimulates hair follicles – accelerating the hair transition from the resting phase (telogen) to the growth phase (anagen)
• Improves scalp blood flow – delivering more oxygen and nutrients to hair follicles
• Regenerates the scalp – supporting the treatment of inflammatory conditions, normalizing skin functions, and strengthening its structure

The result is a noticeable reduction in excessive hair loss, strengthening of hair, and gradual thickening.

Who is the treatment recommended for?

The I-PRF treatment for the scalp is recommended for individuals who:

• Have noticed excessive hair loss (both sudden and chronic)
• Are dealing with androgenic alopecia (both men and women)
• Are experiencing hair weakening and thinning due to stress, pregnancy, hormonal disorders, or infections
• Want to strengthen transplanted hair or prepare for transplantation
• Seek an alternative to pharmacological therapy and synthetic trichological preparations
• Have a scalp prone to inflammatory conditions, flaking, or dryness

Effects of the I-PRF treatment on the scalp:

• Reduction in excessive hair loss → by activating hair follicles and improving their nutrition
• Acceleration of new hair growth → noticeable hair thickening within 8-12 weeks
• Strengthening hair structure → hair becomes thicker, stronger, and more resistant to external factors
• Improved scalp blood flow → better oxygenation and metabolism of hair follicles
• Normalization of skin functions → alleviation of inflammation, reduced itching, improved moisturization
• Long-term regenerative effects → thanks to gradual release of growth factors
• Possibility of combining with other trichological therapies → e.g., mesotherapy, carboxytherapy, biomimetic peptides

Treatment frequency

• A single treatment can effectively support scalp condition, especially after an acute episode of hair loss.
• For optimal results, a series of 3-4 treatments every 3-4 weeks is recommended, followed by maintenance treatments every 6 months.

Why is it worth it?

I-PRF treatment is a safe and effective method for scalp rejuvenation and hair growth stimulation. As an autologous therapy – based solely on components derived from the patient's own blood – it is free from allergy risks and side effects, while being in line with the body's natural physiology.

It is an ideal solution for individuals looking for natural but advanced methods to combat hair loss and hair weakening.

Natural Skin Rejuvenation and Advanced Skin Regeneration

Autologous treatments based on platelet-rich fibrin I-PRF are one of the most effective methods of natural rejuvenation and skin reconstruction, highly valued in both aesthetic and regenerative medicine. A series of 3 I-PRF treatments allows for intensive tissue remodeling - not only smoothing wrinkles but also regaining volume and skin quality in challenging areas such as tear troughs, neck, eyelids, and décolletage.

How does PRP + I-PRF therapy work?

The treatment combines two autologous fractions of the patient's blood:

• Platelet-Rich Plasma (PRP) - contains concentrated blood platelets that immediately activate fibroblasts and other skin cells for regeneration, increase collagen production, and improve microcirculation.
• Platelet-Rich Fibrin (I-PRF) - a modern, three-dimensional form of slow-releasing gel matrix that not only acts regeneratively but also creates a biological "scaffolding" for tissues, gently filling and rebuilding volume.

The result? Synergistic action in the superficial and deep layers of the skin: immediate improvement in firmness and complexion, as well as long-term tissue remodeling.

Who is the series of 3 treatments recommended for?

A series of 3 PRP + I-PRF treatments is recommended for patients who:

• observe progressive signs of skin aging - wrinkles, furrows, sagging, loss of contour
• want to improve the quality of thin, delicate, dehydrated skin - neck, eyes, décolletage
• notice volume loss in areas such as tear troughs, cheeks, temples
• deal with acne scars, stretch marks, or early signs of hair loss
• prefer natural regeneration methods - without artificial substances and the risk of allergies
• expect not only improvement in appearance but also deep structural renewal

Skin Types

The therapy is suitable for:

• thin, atrophic, sagging skin
• dry, dehydrated skin with lost elasticity
• sensitive and reactive skin (due to the autologous nature of the preparation)
• mature skin with signs of photoaging
• skin after intensive dermatological or laser treatments requiring reconstruction

Effects of a series of 3 PRP + I-PRF treatments:

• Visible smoothing of mimic wrinkles and furrows - around the eyes, lips, tear troughs, forehead, and neck
• Improvement in facial contour and lift - subtle lifting effect without surgery
• Skin densification and thickening - better tissue structure, thickness, and resilience, especially in sagging areas
• Reduction of fatigue signs and dull complexion - skin becomes radiant and better oxygenated
• Rebuilding tissue volume - especially in sunken facial areas like cheeks, temples, under the eyes
• Evening out skin tone and reducing shadows - improved microcirculation, brightening around the eyes and cheeks
• Long-lasting skin bio-stimulation - thanks to the slow release of growth factors from fibrin
• Improvement in skin quality in challenging areas - décolletage, neck, lower eyelids
• Rejuvenation and densification of the skin around the eyes - the "open-eyed" effect without the risk of swelling
• Regeneration of tissues affected by acne scars, stretch marks, or hair thinning - improving skin texture and color and stimulating hair follicles
• Natural filling effect without "artificial" volume - the face looks healthy, fresh, but not overdone

Frequency and therapy plan

• For optimal results, a series of 3 treatments is recommended at intervals of 4-6 weeks.
• The effects deepen over time and are long-lasting, allowing natural tissue remodeling to continue even 6-12 months after therapy completion.
• Reminder treatment: every 6-12 months

Why opt for a series of 3 PRP + I-PRF treatments?

• It is the most comprehensive form of skin regeneration - natural, safe, and effective.
• The treatment series not only improves external appearance but genuinely rebuilds skin structure.
• The procedure uses only your cells and plasma, making the risk of allergic reactions nonexistent.
• The effects are multi-level and long-lasting - from better complexion to real skin densification and rejuvenation.
• It is an ideal therapy for those who want to regain freshness and a youthful look without synthetic fillers.

Do you want to restore volume, firmness, and a healthy glow to your skin - without artificial substances and invasive procedures? A series of 3 treatments with I-PRF fibrin is a biological response to your skin's needs - natural, deep, and safe. Visit Ambasada Urody Clinic & Spa for a consultation, where our doctors will tailor the therapy to your skin's needs.