FILLER + TISSUE STIMULATOR
When we get older, we are experiencing loss of hydration of the skin and slow down of cells renewal process, which can cause the reduction of skin’s elasticity, firmness and flexibility. Deeper wrinkles occur, especially around the nose, mouth and sometimes on the chin. At the same time thin layer of fat under the skin, necessary to maintain its elasticity and smoothness, slowly disintegrates. This loss of capacity is particularly noticeable around zygomatic bones area, cheeks and on the outer parts of hands.
COLLAGEN LOSS
In younger skin, collagen fibers are elastic and twisted, and the body produces them in abundance in the dynamically running process of neocolagenesis. With age, collagen "springs" unbend, break, and change their physicochemical properties. The production of new collagen fibers also decreases from year to year (the decrease begins around the age of 25 with the loss of approximately 1.5% of collagen per year).
BIOSTIMULATING FILLERS
Biostimulating fillers is one of the most revolutionary fillers that simultaneously regenerate the growth of collagen, i.e. the fibers supporting the skin, responsible for its tension, elasticity and firmness. It is a stimulator, not a typical filler, i.e. tissue replenishment occurs as a result of cell stimulation, and not the introduction of an "implant". Therefore biostimulating fillers is perfect for preventive treatments that improve the quality of the skin. Proper use of Ellanese allows you to recreate what the skin has lost with age and to correct imperfections to restore the proper proportions of the face and achieve the best possible harmony.
The filling effect is immediate and subtly increases through the strong multiplication of your own collagen. The face does not lose its natural look, and it is rejuvenated every day through a strong revitalization process. This process can be successfully called as being natural for the skin. What does this prove? That after the passed time, your appearance will still please you (your skin will look better than before).
The product is biocompatible with the skin, fully absorbed by the body, does not cause allergies or side effects. Ellanse 'fillers are safe, stable with a specific duration of the filling effect, while improving the quality of the skin by multiplying its own collagen. After a certain period of time, the preparation is completely absorbed during natural metabolic processes.
THE EFFECTS OF THE BIOSTIMULATING FILLERS TREATMENT
- correction of wrinkles and folds
- stimulation of own collagen for long-lasting and natural effects
- rejuvenation of the face, neck and cleavage
- filling gaps in tissues
- improvement of the quality and condition of the skin
- reversing the signs of aging
- providing a more natural and youthful appearance
BIOSTIMULATING FILLERS MAIN TREATMENT AREAS
Threatment prices
Facial Rebuilding, Firming, and Contouring
Calcium hydroxyapatite is a modern tissue biostimulator with a patented composition, identical to the natural hydroxyapatite found in human bones and teeth. Safe and biodegradable, used in medicine for over 25 years, it does not cause allergic reactions and is absorbed naturally. Its stability ensures that exposure to high temperatures, UV radiation, or laser treatments does not diminish its effectiveness.
How does calcium hydroxyapatite work on the face?
The treatment works in two directions, combining the effect of immediate filling with long-term collagen production stimulation:
- Immediate facial contouring - a special gel carrier provides a filling effect that is visible immediately after the treatment.
- Long-term collagen biostimulation - after about 4 months, the gel is gradually removed from the body, and newly formed collagen takes its place, improving the skin's structure and restoring its density.
Calcium hydroxyapatite acts as a biological "scaffold" around which fibroblasts intensively produce new collagen fibers. This thickens the skin, making it more elastic and naturally rejuvenated.
Effects of calcium hydroxyapatite treatment on the face:
- Improvement of facial contours and jawline modeling - the skin becomes tighter, and the facial contours become more defined.
- Lifting of the middle and lower parts of the face - firming of sagging skin, restoring its elasticity.
- Reduction of wrinkles and folds - smoothing of nasolabial folds, marionette lines, and wrinkles in the lower part of the face.
- Restoration of facial volume - filling of sunken cheeks and temples, rejuvenating features and giving the face a more harmonious look.
- Facial shape modeling - subtle enhancement of the cheekbones, improvement of the chin and jawline shape.
- Non-surgical nose correction - gentle reshaping and contouring of the nose.
- Skin rejuvenation around the ears - improving the appearance of sagging earlobes.
Calcium hydroxyapatite is an ideal solution for those who want to improve skin quality, contour facial features, and restore a youthful appearance without the need for invasive surgical procedures. Thanks to the natural biostimulation process, the effects are gradual, long-lasting, and harmoniously integrate with the natural anatomy of the face. The results last for 12-18 months, ensuring an improvement in skin quality and a noticeable rejuvenation of facial features.
Regeneration and volume restoration
A treatment based on polylactic acid is an advanced biostimulating therapy that intensely rebuilds lost tissue volume and improves the quality of facial skin. By strongly stimulating fibroblasts to produce their own collagen, the aging process is slowed down, and the skin regains firmness and natural elasticity.
How does polylactic acid work?
Polylactic acid is not a typical filler - its action involves gradual skin restructuring by stimulating collagen production. After the application of the preparation, skin regeneration and rebuilding occur, leading to:
- Replenishment of lost volume - rebuilds cheeks, temples, and tear troughs.
- Reduction of grooves, wrinkles, and skin folds - smoothens marionette lines, nasolabial folds, and crow's feet.
- Improvement of facial contours - lifts sagging corners of the mouth and restores youthful features.
As a result, the skin becomes firmer, smoother, and appears naturally rejuvenated.
Effects of polylactic acid treatment:
- Restoration of facial volume in areas affected by the aging process
- Reduction of deep wrinkles, nasolabial folds, and marionette lines
- Lifting of cheeks and improvement of facial oval
- Densification and firming of the skin, improvement of its tension
- Filling of tear troughs, improvement of skin structure around the eyes, and reduction of crow's feet
- Smoothing and firming of neck and décolleté skin
- Long-lasting improvement in skin quality and its regeneration through intense collagen stimulation
This treatment is an excellent solution for those who want to not only smooth the skin but also rebuild its structure and achieve a natural rejuvenation effect. Results appear gradually, with full skin remodeling occurring over several months, providing a long-lasting lifting and firming effect.
Immediate Effect and Long-lasting Regeneration
A treatment combining lactic acid and hyaluronic acid is an innovative combination that provides both quick skin smoothing and long-term regeneration. Hyaluronic acid immediately moisturizes and fills wrinkles, giving the face a youthful appearance, while lactic acid stimulates fibroblasts to intensively produce collagen and elastin, leading to gradual skin firming and rebuilding of lost volume.
How does the combination of lactic acid and hyaluronic acid work?
Thanks to the synergy of these two substances, the treatment works in two phases:
- Immediate Filling Effect – hyaluronic acid improves skin tension, intensely moisturizes it, and smooths out fine lines.
- Long-lasting Rebuilding and Biostimulation – lactic acid gradually stimulates the skin to produce collagen and elastin, leading to skin densification, improved elasticity, and increased volume in areas where tissue loss has occurred.
Treatment Effects:
- Quick and natural smoothing of wrinkles and folds
- Restoration of facial volume and reconstruction of tissue losses
- Improvement in firmness, elasticity, and skin tension
- Strengthening of the skin's structure and densification
- Intensive moisturization and nourishment of tissues
- Long-lasting skin regeneration through active production of collagen and elastin
The treatment is particularly recommended for individuals above 40 years old who show signs of loss of firmness, deepening wrinkles, and volume loss in the face. Due to the combination of immediate smoothing effect and deep skin stimulation, the results are natural, long-lasting, and gradually deepening, providing a full regeneration and rejuvenation effect.
Natural Breast Firming and Enhancement
Calcium hydroxyapatite (CaHA) is a substance used in aesthetic medicine as a biostimulator improving skin firmness and structure. Its main action is to stimulate fibroblasts to produce new collagen, resulting in skin densification and improved elasticity. In the context of the breasts, the preparation is most commonly injected into the décolletage area and upper part of the breasts, where it acts as a natural scaffold, supporting tissues and leading to subtle lifting of the breasts. The procedure does not enlarge the breasts but improves their shape, skin tightness, and overall appearance, making the breasts look younger and firmer. The process is gradual – the effect appears within a few weeks and can last up to two years.
Who is this procedure for?
- Women with small or moderate breasts who want to improve their firmness
- Individuals whose skin on the breasts has lost elasticity, e.g., after pregnancy or with age
- Slender women who do not have enough fatty tissue for other breast modeling methods
- Individuals seeking a natural improvement in breast appearance without implants or surgery
Effects of the breast procedure:
- Firming and densification of the skin on the breasts and décolletage
- Subtle lifting of the breasts by improving skin tension
- Stimulation of collagen production, leading to long-term tissue regeneration
- Natural effect without artificial breast enlargement
- Moisturization and rejuvenation of the breast skin
- Results visible for up to 18-24 months
Calcium hydroxyapatite is an excellent alternative for women who do not want to use implants but are keen on improving the appearance and firmness of their breasts in a natural way.
Skin firming, regeneration, and natural reconstruction
Calcium hydroxyapatite is an innovative biostimulating substance used to improve skin quality and restore its volume. Its patented composition, identical to natural hydroxyapatite found in human bones and teeth, ensures high safety of use and lack of allergic reactions. The preparation is biodegradable - gradually absorbed in a natural way, and its stability ensures long-term effects, regardless of exposure to high temperatures, UV radiation, or laser treatments.
How does calcium hydroxyapatite work on the body?
This substance is in the form of microspheres suspended in a highly hydrated gel, allowing it to act on two levels:
- Immediate filling effect - the gel carrier provides quick firming and skin tightening.
- Long-term stimulation of collagen production - after about 4 months, the gel is naturally removed from the body, and newly formed collagen takes its place, rebuilding the skin, increasing its density, and improving its elasticity.
Calcium hydroxyapatite creates a biological "scaffold" for fibroblasts in tissues, stimulating them to intense production of collagen fibers. As a result, the skin naturally thickens and rejuvenates, becoming more elastic and resistant to aging processes.
Effects of calcium hydroxyapatite treatment on the body:
- Visible firming and tightening of the skin - the skin in treated areas becomes more elastic and noticeably tightened.
- Reduction of skin sagging - especially in difficult-to-firm areas such as arms, abdomen, thighs, or knees.
- Skin thickening and densification - the preparation stimulates collagen rebuilding, making the skin thicker and more resistant to the effects of time.
- Smoothing of the skin structure - improvement of overall skin condition, increased elasticity, and evening out the skin's surface.
- Restoration of skin volume on hands - elimination of skin thinning and sagging on the hands, giving them a younger look.
- Natural body shaping - applying the preparation around the buttocks helps improve their shape, firmness, and subtly shape the silhouette.
Treatment with calcium hydroxyapatite is an excellent solution for those who want to improve the condition of their body's skin, firm it, and restore its youthful appearance in a natural and long-term way. Thanks to gradual skin biostimulation, the effects appear subtly and progressively, providing long-lasting and harmonious results that last up to 18-24 months.
Skin firming, regeneration, and natural skin rebuilding
Calcium hydroxyapatite is an innovative biostimulating substance used to improve skin quality and restore its volume. Its patented composition, identical to the natural hydroxyapatite found in human bones and teeth, ensures high safety of use and absence of allergic reactions. The preparation is biodegradable - it gradually absorbs in a natural way, and its stability ensures long-term effects, regardless of exposure to high temperatures, UV radiation, or laser treatments.
How does calcium hydroxyapatite work on the body?
This substance exists in the form of microspheres suspended in a highly hydrated gel, allowing for action on two levels:
- Immediate filling effect - the gel carrier provides rapid firming and improvement in skin tension.
- Long-term stimulation of collagen production - after about 4 months, the gel is naturally removed from the body, and newly formed collagen takes its place, rebuilding the skin, increasing its density, and improving its elasticity.
Calcium hydroxyapatite creates a biological "scaffold" for fibroblasts in tissues, stimulating them to intensively produce collagen fibers. As a result, the skin naturally thickens and rejuvenates, becoming more elastic and resistant to aging processes.
Effects of calcium hydroxyapatite treatment on the body:
- Visible firming and tightening of the skin - the skin in treated areas becomes more elastic and noticeably taut.
- Reduction of skin sagging - especially in hard-to-firm areas such as arms, abdomen, thighs, or knees.
- Skin densification and thickening - the preparation stimulates collagen rebuilding, making the skin denser and more resistant to the effects of time.
- Smoothing of skin texture - improvement in overall skin condition, increased elasticity, and surface leveling.
- Restoration of skin volume on hands - elimination of thinning and sagging skin on hands, giving them a younger look.
- Natural body contouring - using the preparation around the buttocks helps improve their shape, firm and subtly sculpt the silhouette.
Calcium hydroxyapatite treatment is an excellent solution for those who want to improve the condition of their body skin, firm it, and restore its youthful appearance naturally and in the long term. Thanks to gradual skin biostimulation, the effects appear subtly and progressively, providing long-lasting and harmonious results that last for 18-24 months.
Intelligent facial regeneration and modeling in one treatment
Ellansé is a modern aesthetic medicine procedure that combines volumetric action with skin biostimulation. It belongs to the new generation of fillers that not only improve facial contours but also strongly stimulate natural biological renewal processes. The treatment is safe, effective, and long-lasting – the effects last from one to even three years, depending on individual needs and the type of product used. Thanks to this, Ellansé gains the trust of patients and recognition of doctors worldwide.
How does the treatment work?
Ellansé works in two stages:
- Immediate filling and modeling effect – the product restores lost volume, smooths wrinkles, and improves facial proportions.
- Gradual skin biostimulation – the microspheres of polycaprolactone (PCL) contained in the product activate fibroblasts to produce new collagen and elastin. These proteins are responsible for the firmness, elasticity, and youthful appearance of the skin.
Thanks to this, Ellansé not only "fills in" but also regenerates the skin from within, rebuilding its structure and improving quality at the cellular level.
When to undergo the treatment?
Ellansé treatment is dedicated to people who:
- notice loss of volume, elasticity, and firmness in the face,
- expect not only an immediate effect but also long-lasting improvement in skin condition,
- want to maintain a natural appearance without a fake look,
- are looking for an alternative to traditional hyaluronic acid-based fillers,
- value the lasting effect and the skin-stimulating biological action.
It is an ideal solution for demanding, informed patients who prioritize quality.
Treatment effects
- Facial contour modeling and filling of volumetric deficits
- Smoothing of nasolabial folds and wrinkles
- Visible improvement in firmness, elasticity, and skin density
- Natural rejuvenation effect without overcorrection
- Fresh, healthy, and radiant skin appearance
- Regeneration through activation of new collagen and elastin production
- Accumulating effect over time – the skin looks better and better in the months following the treatment
Patients often emphasize that their face looks younger but very natural after the treatment – as if it regained its former freshness without being artificially "filled in."
Treatment frequency
Ellansé is a one-time procedure whose effects last significantly longer than with standard fillers. Different variants of the product are available, tailored to the patient's expectations:
- Ellansé S – effect up to 12 months
- Ellansé M – up to 24 months
- Ellansé L – up to 36 months
The treatment does not require a series of repetitions or frequent visits, making it a convenient and long-term solution for individuals valuing comfort and durability.
We perform procedures on preparations
Collagen stimulation, volume restoration, improvement of skin firmness and quality
Sculptra is a renowned, biostimulating preparation based on poly-L-lactic acid (PLLA), considered one of the most effective collagen stimulators in aesthetic medicine. It works not by mechanical filling, but by activating fibroblasts to produce new collagen, resulting in natural firming, densifying, and lifting of the skin.
The preparation is completely absorbable, and the effects appear gradually - resulting in a subtle, harmonious, and long-lasting rejuvenation.
Characteristic features
- Active substance: poly-L-lactic acid (PLLA)
- Mechanism of action: stimulation of own collagen production
- Gradual effect - skin rejuvenation without drastic changes
- Long-lasting results - up to 2 years
- Biocompatible and absorbable - without the risk of permanent changes
- Lifting effect without artificial volume - restores the skin's natural structure
Application
Sculptra works perfectly for patients with signs of volume and firmness loss in the skin, as well as in the therapy of sagging and tissue depressions. Areas of application:
- cheeks
- temples
- jawline
- submental area
- lower parts of the face
- body areas: buttocks, arms, décolletage
Effects
- Stimulation of fibroblasts for collagen synthesis
- Natural firming and improvement of skin elasticity
- Restoration of lost volume
- Improvement of skin quality and density
- Lifting effect without "overfilling" appearance
Duration of effect
On average 18-24 months, with the recommendation to undergo a series of 2-3 treatments at intervals of 6-8 weeks
Collagen stimulation, volume and density rebuilding of the facial and body skin, with a natural, long-lasting rejuvenating effect
AesPlla® is a modern, biostimulating preparation based on L-polylactic acid (PLLA), which works by activating fibroblasts to produce collagen, gradually restoring the volume, density, and firmness of the skin in a natural way.
PLLA molecules are fully biocompatible and biodegradable, and their breakdown in the body results in the formation of carbon dioxide, water, and sugars, making AesPlla® completely safe.
Key characteristics
- Active substance: L-polylactic acid (PLLA)
- Mechanism of action: long-term stimulation of collagen production
- Biocompatible and absorbable - minimal risk of allergic reactions
- Natural tissue rebuilding without the "overfilled" effect
- Longest-lasting biodegradable filler (PLLA - FDA approved)
- Gradual and subtle effect - without sudden changes in appearance
Application
AesPlla® is recommended for rebuilding volume and density of the skin in facial and body areas, especially in patients with visible sagging, depressions, and loss of firmness. Areas of application:
- cheeks
- temples
- jawline
- lower face
- buttocks, arms, thighs
Effects
- Active stimulation of fibroblasts for collagen production
- Gradual rebuilding of lost volume
- Improvement in firmness, elasticity, and skin density
- Natural effects without the risk of product migration
Duration of effect
On average 18-24 months, after a series of 2-3 treatments with intervals of 6-8 weeks
Deep wrinkles, volume loss, skin sagging, biostimulation, and facial and body contouring
Lenisna is a modern hybrid filler and tissue stimulator that combines the immediate effect of hyaluronic acid with the long-term regenerative action of poly-D,L-lactic acid (PDLLA). The product is designed to treat deep wrinkles, loss of volume, skin sagging, as well as for sculpting facial and body contours.
It works in two phases: providing quick tissue smoothing and filling, followed by activating fibroblasts for intensive collagen production, restoring skin firmness and elasticity gradually, naturally, and long-lastingly.
Key Features
- Hyaluronic acid: 30 mg - immediate filling effect
- Poly-D,L-lactic acid (PDLLA): 170 mg - long-term collagen stimulation
- Hybrid technology - HA + PDLLA combined in one injection
- No need for massage - convenient and predictable procedure
- Safe, biocompatible composition
- Long-lasting effect - lasts up to 24 months
Application
Lenisna is recommended for patients showing signs of volume loss, elasticity, and firmness of the skin, both on the face and body. Areas of application include:
- Wrinkles and folds
- Sunken cheeks
- Skin depressions and sagging
- Drooping facial features
- Inner thighs
- Abdomen
- Buttocks
- Arms
Action
- Tissue filling and wrinkle smoothing (HA effect)
- Intensive collagen stimulation and skin densification (PDLLA action)
- Improvement in skin firmness, tension, and density
- Lift effect without surgery
- Natural, gradual rejuvenation outcome
Effect Duration
Up to 24 months after a series of 2-3 treatments performed every 6-12 weeks
Volumetry, contour modeling, collagen stimulation, and long-lasting smoothing of deep wrinkles
Radiesse is an innovative next-generation filler and tissue stimulator that provides immediate volumetric effects and long-term skin rejuvenation by stimulating natural collagen production. It contains calcium hydroxyapatite (CaHA) microspheres - a substance naturally found in the human body (in bones and teeth).
CaHA particles create a biological "scaffolding" for fibroblasts, which produce new collagen - as a result, the skin becomes denser, firmer, and more elastic, while facial contours are sculpted in a natural and lasting way.
Key features
- Active ingredient: calcium hydroxyapatite (CaHA) microspheres
- Immediate volumetric effect after administration
- Long-lasting action - collagen stimulation by the body
- Biocompatibility and safety - CaHA naturally occurs in the body
- Ability to sculpt and shape facial contours
- Duration of effect: from 12 months up to 5 years (depending on the patient and area)
Application
Radiesse is ideal for modeling and restoring volume in the lower and mid-face regions, as well as correcting deep wrinkles. Areas of application include:
- Jawline
- Naso-labial folds
- Marionette lines
- Cheekbones
- Chin
- Non-surgical nose correction
Effects
- Deep tissue and wrinkle filling
- Facial contour modeling
- Biostimulation - production of new collagen
- Improvement of skin density, firmness, and elasticity
- Natural and long-lasting effect without overcorrection
Duration of effect
From 12 up to 60 months, depending on the injection area, technique, and individual patient characteristics
Cheek and jaw modeling, filling of wrinkles and grooves, biostimulation, and skin densification
Crystalys is one of the strongest biostimulators on the market, based on a high concentration of calcium hydroxyapatite (CaHA) microspheres. The product combines an immediate filling effect with long-term stimulation of collagen production, resulting in a natural and lasting rejuvenation effect.
It works in two stages: the gel base (CMC) provides immediate lifting and tissue filling, while the CaHA particles (55.7%) create a scaffold for fibroblasts, stimulating the skin for intensive collagen rebuilding. Due to its structure, Crystalys harmoniously binds with tissues and ensures a long-lasting, natural effect of volume enhancement without overcorrection.
Key Features
- Active substance: 55.7% calcium hydroxyapatite (CaHA) microspheres
- Gel base (CMC) – immediate filling effect
- Biostimulation of fibroblasts – long-term collagen production
- Two-phase action – quick effect + skin regeneration
- Biocompatible and biodegradable – natural breakdown in the body
- Effect lasts on average 18–24 months
Application
Crystalys is recommended for volume rebuilding, facial contour modeling, and skin quality improvement. Areas of application include:
- cheeks
- jawline
- nasolabial folds
- marionette lines
- dorsal hands
- deep skin layers and subcutaneous tissue
Operation
- Immediate skin lifting and firming
- Long-term stimulation of collagen production
- Facial contour improvement
- Filling of deep wrinkles and folds
- Natural and harmonious tissue integration
Effect Duration
On average 18–24 months, thanks to long-term collagen stimulation
Expert opinion
Hybrid fillers are a modern aesthetic concept that allows us to work not only on the shape and contour of the face, but also on the quality and structure of the skin. They combine modeling effects with biostimulating effects – which means that we are simultaneously working on proportions and actual skin rejuvenation.
As a doctor specializing in facial aesthetics for years, I know how important it is to have a sense of proportion, symmetry, and expression. Hybrid fillers allow me not only to restore volume where it has been lost, but also to stimulate the skin for regeneration – densification, firming, and increasing its resistance to aging. I use them where we aim for more than just filling – in the central part of the face, when rebuilding the contour of the jaw, cheeks, temple area, or chin. The effects are subtle but noticeable – features become calmer, the face looks younger, but naturally. Hybrid fillers are solutions that provide aesthetic results here and now, but at the same time support the skin in the longer term. This combination of immediate contour improvement with deep skin remodeling makes the face look younger – naturally, harmoniously, without exaggeration.
For me, this is one of the key directions in modern aesthetic medicine – because it allows us to counteract signs of aging in a way that strengthens the skin from within, without disrupting its natural rhythm.