Autologous fillers

Platelet-rich plasma mesotherapy + volume restoration with plasma gel

CGF Harmony is an advanced regenerative treatment combining the action of platelet-rich plasma with autologous albumin gel (Activated Plasma Albumin Gel), obtained from the patient's blood proteins. The therapy allows for intensive skin stimulation and subtle facial contouring – using completely natural material, without the use of synthetic fillers.

The treatment combines needle mesotherapy with volumetry, restoring volume in strategic areas of the face. By utilizing the CGF Harmony set, the doctor obtains two fractions: a liquid one with stem cells and growth factors, and a gel one that serves as a biological filler. This approach blurs the lines between aesthetic and regenerative medicine, acting not only on the surface but also deeply rebuilding the skin structure.

Who is the treatment intended for?

• for individuals with flaccid, thin, and dehydrated facial skin,
• with visible wrinkles and furrows (e.g., nasolabial, marionette lines),
• for natural facial contouring,
• for skin in need of intensive regeneration, nourishment, and improved firmness,
• as an alternative to synthetic fillers, for patients who appreciate autologous solutions,
• for significant volume loss e.g., in the cheek area, temples, tear troughs.

How does CGF Harmony work?

Two active fractions are obtained from the patient's blood:

• Platelet-rich plasma with growth factors and stem cells, which biostimulates the skin – promoting skin regeneration, increasing collagen and elastin production, and improving microcirculation.
• Autologous albumin gel (Activated Plasma Albumin Gel) – acts as a natural filler, providing volumetric effects and restoring volume in selected areas of the face. Its structure ensures prolonged release of growth factors, intensifying and prolonging the regeneration effect.

The combination of both formulas achieves both skin rejuvenation and subtle lifting effects.

Effects of CGF Harmony treatment:

• Visible rejuvenation of facial skin – skin becomes fresher, more radiant, and noticeably rested after the first treatment.
• Increased firmness, elasticity, and flexibility – skin tightening due to fibroblast activation and collagen and elastin production.
• Smoothing of wrinkles and furrows – significant reduction in mimic lines, nasolabial grooves, and gravitational wrinkles.
• Natural facial volume restoration – restoring a youthful facial contour with a gentle volumetric effect, without the artificial "filling" effect.
• Tissue lifting and facial contour improvement – the gel acts as a natural scaffold, supporting the skin structure and gently lifting sagging areas.
• Strong skin regeneration and biostimulation – improving microcirculation, oxygenation, and nourishment of the skin at a cellular level.
• Densification and thickening of thin and flaccid skin – especially in challenging areas such as lower eyelids, temples, or the back of hands.
• Evening out skin tone and brightening complexion – reducing dullness, discoloration, and signs of fatigue, resulting in radiant skin.
• Delaying aging processes – skin cell activation slows down signs of aging and improves long-term skin condition.
• Comprehensive "natural lifting" effect – skin appears younger without an exaggerated effect, making this treatment ideal for individuals valuing subtlety and facial harmony.

Treatment frequency

• A recommended series consists of 3 treatments spaced 6 weeks apart, depending on skin condition and desired results.
• To maintain treatment effects, a touch-up treatment every 6-12 months is recommended.

Why choose CGF Harmony?

CGF Harmony is a treatment for those expecting natural, effective, and safe skin rejuvenation methods – without surgical intervention or the use of artificial products. It combines mesotherapy, biostimulation, and gentle volumetry into one, using only material derived from the patient's body.

Thanks to the synergy of plasma and albumin gel, the effects are visible, long-lasting, and in line with skin physiology – a modern, biological alternative to traditional aesthetic procedures.

Autologous next-generation tissue filler

The SKIN UP procedure is an innovative regenerative medicine treatment that harnesses the potential of a patient's own blood to rebuild volume and structure in the skin. It serves as an alternative to traditional synthetic fillers - completely biocompatible, safe, and natural. Thanks to modern technology for plasma separation and thermal processing, an autologous gel with consistency and properties similar to hyaluronic acid fillers is obtained, but without the risk of allergic reactions, swelling, or overcorrection.

SKIN UP is not just an aesthetic procedure but primarily a regenerative therapy that activates the skin's natural repair processes. Growth factors in platelet-rich plasma activate fibroblasts to produce collagen, elastin, and hyaluronic acid, leading to lasting strengthening and densification of tissues. As a result, the skin regains youthful elasticity, firmness, and volume, with facial features becoming harmonious and rested.

The procedure is performed in one visit - fully autologous, sterile, and safe. The resulting material can be used in various areas: from facial contouring, cheek corrections, nasolabial folds, temple and jawline areas, to lip revitalization or hand rejuvenation.

How the procedure works - mechanism of action

Below is a step-by-step description of the process:

• Patient's blood collection - usually 10-20 ml.
• Centrifugation of blood in special tubes to obtain platelet-rich plasma (PRP).
• Subsequently, part of the plasma undergoes a heating process ("gelling") in a dedicated device such as the "Plasma Gel Maker" at around 80°C for about 10 minutes, followed by cooling for about 8 minutes - resulting in autologous gel with the right consistency.
• Material homogenization by passing through syringes - allows for obtaining various versions (hard, medium, soft) depending on the area's needs.
• Introduction of the resulting autologous gel - usually with a cannula or needle - into the selected facial and/or body areas for volume correction, contouring, and tissue regeneration.

The mechanism of action is based on both volumizing (filler gel filling gaps) and regenerative action (growth factors, platelet-rich plasma stimulating tissue repair).

Who is the procedure recommended for and what issues can it address?

This procedure is particularly recommended for individuals who:

• Have visible loss of skin volume (e.g., in cheek, temple, or jaw areas).
• Observe sagging of facial contours - jawline sagging, nasolabial folds.
• Desire a "soft lifting" effect without synthetic fillers.
• Have thin skin prone to swelling or are allergic/unwilling to use traditional hyaluronic acid-based fillers.
• Want to improve the condition of hands, lips - areas challenging for traditional filling therapy.
• Are willing to invest in regenerative treatments that combine aesthetic effects with skin structure improvement.

The procedure does not replace surgical facelift - in cases of advanced sagging or deep wrinkles, combination with other technologies may be necessary.

Skin types

The treatment can be used on most skin types - particularly beneficial if the skin is:

• Thin, with visible subcutaneous tissue loss;
• Beginning to lose firmness or volume ("structural wrinkles", sagging jawline);
• Prone to swelling with traditional fillers - in such cases, autologous material may be a better choice.

As an expert, I emphasize that each skin requires individual assessment - a consultation with a cosmetic doctor will help determine: the product variant (soft/medium/hard), application technique, and potential combination with supporting therapies.

Effects of the SKIN UP procedure

• Visible facial volume rebuilding - e.g., in cheek or temple areas, with autologous gel filling → the result is natural as it comes from the patient's blood.
• Improvement of facial contour - the jawline becomes more defined, "chubby cheeks" reduce → the skin looks younger and more harmonious.
• Smoothing wrinkles and skin folds - autologous gel and growth factors support tissue repair, leading to less visible mimic lines.
• Enhancement of skin density and quality - platelet-rich plasma content makes the skin firmer, more elastic, with better tension.
• Very good tolerance - as the material is autologous, the risk of allergic reactions or swelling is lower than with some synthetic fillers.
• Regeneration effect - besides filling, the skin is biologically stimulated for repair and structural strengthening → result is not only aesthetic but also functional.
• Possibility of application in various areas - from the face, through lips, hand dorsum, to contouring smaller body parts - thanks to the ability to vary the gel's consistency.

Frequency of treatments (usage plan)

To ensure optimal and lasting results, I recommend the following plan:

• First treatment as a full material application - covering the indicated area.
• After about 3 months, evaluate the effect and possibly supplement - especially if some autologous material has been partially resorbed.
• Typically, after 2-3 treatments (spaced around 3 months), we achieve an effect lasting about a year.
• In the following years, the treatment can be repeated once a year or as per individual dermatological assessment.

Each plan is determined by a specialist - considering the patient's age, skin condition, expectations, and treatment technique.

Number of areas that can be treated depending on the amount of autologous filler used

The treatment range depends on the amount of used filler, which is measured in syringe-ampoules. This allows for precise therapy adjustment to skin needs and the desired aesthetic effect.

• 1 syringe - enables treatment of 1 larger area (e.g., cheeks, neck, forehead, décolletage) or 2 smaller areas (e.g., eye area + nasolabial fold).
• 2 syringes - allow for comprehensive facial therapy (e.g., cheeks + eye area + forehead) or face and neck, providing significant skin smoothing and density improvement.
• 3 syringes - enable full revitalizing therapy for face, neck, and décolletage or face and hands, offering rejuvenation effect on multiple areas simultaneously.

Example: Simultaneous treatment of cheeks, tear troughs, and chin - to achieve a natural smoothing and shaping effect on the lower face - typically requires 2-3 syringes, depending on the initial skin condition and expected results.

During the consultation, the specialist will assess skin needs precisely and propose an optimal treatment plan - to achieve a harmonious, natural effect without overcorrection.

Why choose the SKIN UP procedure?

Choosing SKIN UP is a conscious decision - it combines aesthetics with regenerative medicine, providing an advantage over traditional fillers:

• The material comes from the patient's blood - minimizing reaction risks and increasing safety.
• The effect is not only filling but also regenerative - meaning the skin not only looks better but functions better.
• You can adjust the consistency (hard/medium/soft) and technique, achieving a natural look without an "overfilled" effect.
• Excellent option for patients with filler allergies, tendency to swell, or desiring comprehensive anti-aging action.
• In our clinic, Ambasada Urody Clinic & Spa in Warsaw, we provide thorough diagnostics, protocol selection, and full post-treatment support - ensuring client comfort and peace of mind.

By choosing SKIN UP, you invest in long-term effects - not only visual but also structural and skin health benefits.