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Bio-compatible RH collagen + hyaluronic acid.

Karisma is a breakthrough tissue bio-stimulator that stimulates the body for natural regeneration, effectively improving the elasticity, firmness, and quality of the skin. It is the only one to contain Rh collagen, identical to human collagen, ensuring excellent tolerance and high effectiveness. This collagen is sourced from silkworm farms, where silkworms synthesize type I collagen through modern biotechnological technology, necessary for skin reconstruction. Upon introduction of the preparation into the skin, there is an intense reconstruction of the extracellular matrix, leading to fibroblast stimulation - cells responsible for producing new collagen and elastin fibers. This process enhances the skin structure, densifies it, and strengthens it, making it more tense, smooth, and resistant to aging processes.

HOW DOES THE KARISMA TISSUE STIMULATOR WORK?

  • Provides bio-compatible Rh collagen - when directly applied to the skin, recombinant Rh collagen is identical to human collagen, which means that the body does not treat it as a foreign substance. This collagen effectively integrates with the skin matrix, strengthening its structure and improving firmness.
  • Stimulates fibroblasts to produce collagen and elastin - in addition to directly supplementing collagen, Karisma stimulates the skin's natural regenerative mechanisms. Fibroblasts - cells responsible for creating structural proteins - begin to intensively produce new collagen type I and elastin, leading to improved skin density and firmness.
  • Rebuilds the extracellular matrix (ECM) - collagen delivered to the skin strengthens the structure of the extracellular matrix, which acts as the skin's scaffold. This makes the skin more resistant to aging processes and loss of firmness.
  • Intensely moisturizes the skin - the hyaluronic acid in Karisma acts as a natural water reservoir, binding water molecules in the skin. This not only improves its hydration but also further supports the function of collagen, which functions better in a properly hydrated environment.
  • Accelerates skin regeneration - the delivered collagen and stimulation of fibroblasts lead to intense cell renewal. This results in faster skin regeneration, making scars and minor damages less visible, and the skin gains a uniform structure and a healthy appearance.
  • Increases skin density and improves its firmness - the combination of collagen supplementation and stimulation of its production makes the skin thicker, more elastic, and less susceptible to sagging.

Karisma not only provides collagen to the skin but also stimulates the body to naturally produce it, resulting in a long-lasting and multi-dimensional rejuvenating effect. This combination of replacement action (supplementing missing collagen) and stimulating action (activating regenerative processes) leads to a significant improvement in skin quality and structure.

KARISMA EFFECTS

  • Skin rejuvenation and revitalization – Karisma effectively improves the quality of facial, lip, neck, décolletage, and hand skin. The skin becomes more radiant, elastic, and firm, resulting in a fresh, rested appearance.
  • Facial contouring and subtle lifting effect – By stimulating collagen and elastin production, the skin gains greater firmness and elasticity. The facial contour is subtly sculpted, and the contours become more defined.
  • Wrinkle reduction and skin smoothing – Karisma's biostimulator acts on the deep structures of the skin, filling in fine lines and reducing the visibility of wrinkles. The skin looks younger and more toned.
  • Improvement in skin moisturization and hydration – Hyaluronic acid in the product intensely binds water, making the skin more moisturized, soft, and supple. This effect is particularly important for dry, dull, and tired skin.
  • Increased skin density and cohesion – By rebuilding the extracellular matrix, the skin becomes thicker, more resistant to loss of firmness, and less susceptible to external factors.
  • Reduction in pore visibility – The skin becomes more uniform, smooth, and has an even texture. This effect contributes to improving the overall appearance of the complexion, giving it a healthy and radiant glow.
  • Smoothing of acne and post-traumatic scars – Karisma supports regenerative processes, making scars less visible, and the skin acquires a more uniform color and texture.
  • Stretch mark reduction and improvement in skin elasticity – Collagen and elastin stimulation make the skin more elastic, and stretch marks less visible. This effect is particularly beneficial for individuals after weight loss or pregnancy.

Karisma Biostimulator is an innovative solution for individuals who desire natural skin regeneration, smoothing, and rejuvenation without the need for invasive procedures.

WHEN TO USE TISSUE BIOSTIMULATOR KARISMA?

The Karisma biostimulator is effective in cases where the skin requires regeneration, rebuilding, and improvement in quality. Indications for the treatment include:

  • Loss of firmness and elasticity of the skin - when the skin loses its elasticity, becomes saggy and less taut, Karisma stimulates the production of collagen and elastin, restoring its density and youthful appearance.
  • Visible wrinkles and signs of aging - if the skin starts showing initial signs of aging, such as fine lines and wrinkles, the treatment stimulates regeneration, firms the skin, and smoothens wrinkles.
  • Dry, weakened skin - when the skin is dull, dry, and dehydrated, Karisma intensely moisturizes and strengthens its structure, improving comfort and appearance.
  • Acne and post-traumatic scars - in the case of scars of various origins, the biostimulator supports regenerative processes, replenishing collagen deficiencies and smoothing the skin's structure.
  • Stretch marks and skin sagging on the body - when the skin in areas such as the décolleté, neck, hands, or areas affected by stretch marks loses density, Karisma rebuilds its structure and improves elasticity.
  • Facial oval weakening - when the facial contour begins to blur, and the skin loses its distinct line, Karisma helps gently reshape the face, improving its shape and tension.
  • Anti-aging prevention - for individuals who want to prevent premature loss of collagen and elastin to maintain a youthful skin appearance for longer.

The Karisma treatment is an excellent solution for individuals with visible signs of aging as well as those who want to improve skin quality and prevent premature aging.

WHY CHOOSE BIOSTIMULATOR KARISMA?

  • Dual action – replenishes and stimulates collagen – Karisma not only provides bio-identical Rh collagen identical to human, but also stimulates fibroblasts for intense production of new collagen and elastin, ensuring long-lasting rejuvenation effects.
  • Natural and safe composition – the biostimulator is based on recombinant human collagen obtained from silkworm cultures, making it fully biocompatible, well-tolerated, and does not cause allergic reactions.
  • Fast and long-lasting effects – after just two treatments, the skin becomes visibly firmer, tighter, and radiant, with results lasting for many months.
  • Minimally invasive method – the procedure is safe, comfortable, and does not require lengthy recovery, allowing a quick return to daily activities.
  • Natural lifting effect – Karisma works subtly, improving skin tension, facial contours, and elasticity, without the risk of an overdone look.
  • Comprehensive skin action – the biostimulator not only firms and regenerates but also improves hydration, reduces the visibility of pores, scars, and fine lines, evening out the skin texture.
  • Works on multiple levels – rebuilds the skin both on the surface and in its deeper layers, ensuring long-lasting effects.
  • Universal application – Karisma can be used on the face, neck, décolletage, hands, or other body parts requiring regeneration and firming.

Thanks to the unique combination of collagen and hyaluronic acid, the biostimulator Karisma provides an excellent alternative to more invasive procedures, ensuring long-lasting and natural rejuvenation effects and improving skin quality.

CONTRAINDICATIONS TO THE KARISMA PROCEDURE

The Karisma biostimulator is a safe product, however, like any injectable treatment, it has specific contraindications. It should not be used in cases of:

  • Active skin infections - such as herpes, pustular acne, bacterial or fungal infections at the injection site. -
  • Antibiotic therapy - it is recommended to wait 14 days after completing the treatment to allow the body to fully regenerate and reduce the risk of a weakened response to the treatment.
  • Pregnancy and breastfeeding - as there are no studies confirming the safety of use during this period. -
  • Autoimmune diseases - they can affect the body's response to the product injected.
  • Tendency to form keloids - there is a risk of abnormal skin healing after the treatment.
  • Cancer - both during treatment and in the recovery period.
  • Unstable diabetes - healing disorders may affect the effectiveness of the treatment.
  • Taking anticoagulant medications - increased risk of bruising and hematomas.
  • Allergy to the product's ingredients - although Karisma is well tolerated, it is advisable to consult a doctor before the treatment.

POST-THERAPY RECOMMENDATIONS FOR KARISMA

After undergoing the Karisma procedure, it is important to follow several rules to ensure optimal conditions for skin regeneration and achieving the best results.

  • Avoid touching and massaging the injection sites for the first 24 hours to prevent displacement of the product. 
  • Avoid intense facial expressions for the first 24 hours to ensure even absorption of the product.
  • Do not use makeup for at least 12 hours after the procedure to minimize the risk of infection.
  • Avoid sun exposure, tanning beds, and saunas for 7 days - heat can cause irritation and delay skin regeneration.
  • Avoid swimming pools and gyms for 48 hours - moisture and sweat can increase the risk of infection.
  • Refrain from consuming alcohol and intense physical exercise for 24 hours - they can worsen swelling and increase the risk of bruising.
  • Maintain proper skin hydration - drinking plenty of water and using gentle moisturizing creams will support the regeneration process.
  • Adhering to the above recommendations allows for the quick and effective action of the product, ensuring the best results in skin biostimulation and regeneration.

Threatment prices

Karisma collagen therapy

New generation of collagen biostimulation – restoring skin quality from within

Karisma collagen therapy is an advanced regenerative treatment that does not mask the symptoms of aging, but restores the skin's physiological structure and function. Thanks to the synergy of active ingredients, there is a real reconstruction of the extracellular matrix, which translates into an improvement in skin quality in a natural, harmonious, and long-lasting way. This solution is particularly valued by patients expecting subtle yet clear rejuvenation effects – without an overdone effect.

The effect of the therapy builds up gradually, which is its huge advantage – the skin does not change suddenly, but regains its biological youth with each visit. This is an investment in skin quality, not just its temporary appearance.

How does Karisma collagen therapy work?

The mechanism of action is based on multi-level biostimulation and skin reconstruction:

  • Activation of fibroblasts → recombinant Rh collagen acts as a „biological signal”, initiating the production of new type I and III collagen
  • Stimulation of procollagen synthesis → rebuilding skin structure from the level of the extracellular matrix
  • Intense hydration → hyaluronic acid binds water and improves the metabolic environment of cells
  • Protection against degradation → carboxymethylcellulose stabilizes hyaluronic acid and limits its breakdown
  • Improved intercellular communication → increased biological activity of the skin
  • Regeneration and reconstruction of tissues → particularly in damaged areas (scars, loss of volume)

This action leads to the remodeling of the skin in a physiological rather than mechanical way. As a result, tissues become denser, more elastic, and resistant to aging processes.

Who is the treatment recommended for?

The therapy was designed for people who expect a qualitative improvement in the skin, and not just a filling effect:

  • flaccid, thin skin with loss of firmness
  • first and intermediate signs of aging
  • mimic and static wrinkles
  • acne and post-traumatic scars
  • dehydrated, tired skin, lacking radiance
  • loss of volume in the face and around the mouth
  • anti-aging prophylaxis in younger patients

The treatment also works perfectly as an element of combined therapies – it prepares the skin for more advanced procedures or strengthens their effects.

Areas of application

The treatment is widely used in aesthetic medicine, especially in areas requiring regeneration:

  • face → improvement of tension, smoothing, and revitalization
  • mouth area → subtle improvement of contour and skin quality
  • scars → leveling of structure and tissue regeneration
  • neck → increasing elasticity and reducing flaccidity
  • decolletage → rebuilding density and improving skin appearance

The ability to work precisely on different areas makes the therapy extremely versatile and tailored to the individual needs of the patient.

Effects of Karisma stimulator therapy

The results are both immediate and long-term – they develop along with the remodeling of the skin:

  • clear improvement in skin firmness and elasticity – tissues regain tension and a more compact structure
  • smoothing of wrinkles – the skin becomes more uniform, and facial features softer
  • reduction of scars – gradual leveling of the skin surface and improvement of its quality
  • intense hydration – the skin regains comfort, softness, and natural radiance
  • improvement of skin density – the effect of a „thicker”, more resistant structure
  • subtle improvement in volume – natural filling without an artificial effect
  • revitalization and illumination – the skin looks healthy, fresh, and younger

The end result is extremely natural – the skin simply looks better, without visible traces of aesthetic interference.

Frequency of treatments (therapy plan)

For optimal results, the following treatment protocol is recommended:

  • series of 2–3 treatments → performed every 4 weeks
  • 1st treatment → intense hydration and activation of regenerative processes
  • 2nd treatment → clear improvement of the structure, smoothing, and thickening of the skin
  • 3rd treatment → consolidation of effects and long-term tissue remodeling

The first effects are visible after just one session, while a full series ensures lasting improvement in skin quality.

  •  a maintenance treatment is recommended every 6–12 months – it allows you to maintain the effects and slow down the aging process

The regularity of therapy translates directly into the stability and longevity of the results.

Why is it worth choosing Karisma therapy at Ambasada Urody Clinic & Spa?

The effectiveness of biostimulation depends not only on the preparation, but primarily on the precision of its application and the experience of the specialist. At Ambasada Urody, we combine aesthetic medicine with a deep understanding of the biological processes of the skin.

  • individual patient qualification → selection of a protocol tailored to the skin's needs
  • experienced specialists → precise application technique and therapy safety
  • holistic approach → possibility of combining with other procedures for maximum effects
  • working on the highest quality preparations → confirmed effectiveness and safety
  • natural results → aesthetics consistent with facial anatomy and physiology

This is a therapy for conscious people who expect a real improvement in skin quality – not a temporary effect. Properly conducted biostimulation becomes one of the most effective tools of modern anti-aging.

1 vial
1 400 PLN
2 vials
2 800 PLN 2 400 PLN

We perform procedures on preparations

Karisma Rh Collagen Face
Karisma Rh Collagen Face

Biostimulation and natural skin regeneration, improvement of firmness and elasticity, smoothing of wrinkles

Karisma Rh Collagen Face is a modern biostimulator and so-called soft filler, classified as a Class III medical device, created for the complete natural rebuilding, regeneration, and rejuvenation of the skin. The product is based on a unique formula combining a polypeptide chain of type I collagen α1, high molecular weight hyaluronic acid, and carboxymethylcellulose (CMC). The collagen used in Karisma is obtained using the innovative NEOSILK® technology (from silk threads), making it 100% biocompatible and non-animal derived.

Key Features

  • Polypeptide chain of type I collagen α1 - obtained from silk, tissue-compatible, non-animal origin, supports the formation of correct collagen structures and strongly stimulates fibroblasts
  • High molecular weight hyaluronic acid - immediate filling effect and improvement of the quality of the extracellular matrix
  • CMC (carboxymethylcellulose) - antioxidant action, protection against hyaluronic acid degradation, support of bioregeneration
  • Natural composition - without chemical cross-linking agents
  • Biocompatible and bioavailable - completely safe, does not require allergic tests

Application

  • Biostimulation and skin revitalization
  • Improvement of firmness and elasticity
  • Smoothing of fine lines
  • Improvement in skin quality and density
  • Restoration of natural facial contour

Areas of Application

  • Face
  • Neck
  • Décolletage

Effect

  • Stimulation of fibroblasts for the production of type I pro-collagen
  • Improvement of the extracellular matrix structure and collagen rebuilding
  • Immediate moisturization and gentle filling effect
  • Protection against free radicals and HA degradation
  • Natural skin regeneration and rejuvenation

Duration of Effect

On average 6-12 months, depending on skin condition and number of treatments performed (recommended series: 2-3 treatments every 3-4 weeks)