Mature skin exhibits characteristics of both exogenous aging, conditioned by unfavorable external environment, as well as endogenous one, associated with genetic susceptibility and biological clock. The tissue renewal process is disturbed. The skin gradually becomes thinner, while the stratum corneum thickens, the consequence of which is skin becoming grey and loses its radiance.
Over time, our body goes from anabolism to catabolism, followed by insufficient production of estrogen and progesterone by the ovaries. These changes are reflected in the appearance of our skin. There are various kinds of discoloration and it significantly reduces its elasticity, increasing the amount of deep wrinkles. The process of keratinization stops, which affects the barrier function. The process for producing the intercellular lipid cement in the stratum corneum is not proceeding properly, which leads to excessive drying and flaking of the skin. Also, excessive epidermal water loss causes the look of dry, rough, scaly skin. In the dermis, the fibroblast activity decreases, changes occur between proportion of individual types of collagen and the structure of supporting proteins changes, the consequence of which is a decrease in the flexibility and elasticity of the skin and increase in the amount of wrinkles, as well as sharpening of the facial features. Muscles are weakened and their activity decreases, which adversely affects the look of the skin, its tension.