Needle mesotherapy or microneedling?

14.11.2025
Needling mesotherapy and microneedling are popular aesthetic medicine treatments that support collagen and elastin production in the skin. Although both methods aim to improve skin condition, they differ in techniques, penetration depth, and types of stimuli used during the procedure. Needling mesotherapy works in deeper layers of the skin, while microneedling focuses on regenerating the superficial layer, stimulating natural recovery processes. Find out which method will best meet your needs!
Needle mesotherapy vs. microneedling – a guide

Needle mesotherapy and microneedle mesotherapy are popular treatments used in aesthetic medicine aimed at improving skin condition by stimulating the production of collagen and elastin. The first one involves injecting active substances directly into deeper layers of the skin using fine needles. This allows nutrients to reach exactly where they are most needed.

On the other hand, microneedle mesotherapy utilizes special devices to create micro-punctures on the skin, activating the body's natural regenerative processes. As a result, collagen and elastin production increases, and the skin's structure improves. These devices can be manual or automatic, affecting the precision of the procedure.

Both types of mesotherapy offer unique benefits, making it possible to tailor them to the individual needs of the patient and the expected results. Needle mesotherapy is often chosen for its intensive action on deeper skin layers, while microneedle mesotherapy is great for overall skin improvement.

The decision on choosing the appropriate method should be made after consulting with a qualified aesthetic medicine specialist who will assess the skin condition and propose the most effective therapy tailored to the specific individual.

What are the main differences between needle mesotherapy and microneedle therapy?

The differences between needle mesotherapy and microneedle mesotherapy relate to the method of performing the procedure and the depth of punctures.

  • Needle mesotherapy involves using thin needles to introduce active substances deep into the skin, up to a depth of 3 mm. This allows the ingredients to reach the deeper layers of the skin directly, enabling intensive regeneration.
  • Microneedle mesotherapy uses devices to create micro-punctures at a shallower depth, ranging from 0.5 to 1.5 mm. The goal of this method is to stimulate the skin's natural rebuilding processes by increasing collagen and elastin production. It focuses more on improving the external structure of the skin rather than delivering specific substances deep into it.

There are also differences in patient comfort:

  • Needle mesotherapy can be more painful due to thicker needles and deeper punctures.
  • Microneedle mesotherapy is often better tolerated due to shallower punctures and more uniform action.

The choice of the appropriate mesotherapy method depends on the individual needs of the patient and the expected therapeutic effects.

Needle mesotherapy or microneedling - which method is more effective?

It is not easy to determine which method of mesotherapy - needle or microneedle - is more effective. Each of them has its unique properties, and their effectiveness depends on the specific skin issue and the desired results.

Needle mesotherapy works in deeper layers of the skin, making it ideal for advanced skin regeneration. On the other hand, microneedle mesotherapy focuses on superficial skin layers, improving its structure and supporting natural rebuilding processes.

The effectiveness of both techniques should be assessed based on the individual needs of the patient. Needle mesotherapy is recommended for individuals with more serious skin issues, while microneedle mesotherapy is suitable for those seeking overall skin improvement. It is important to tailor the treatment to the specific requirements of the skin after consultation with a qualified aesthetic medicine specialist.

When is it worth choosing needle mesotherapy?

Needle mesotherapy is an excellent choice when the skin requires deep regeneration and intense hydration. This treatment effectively reduces the visibility of wrinkles, acne scars, and signs of skin aging, such as loss of firmness. Additionally, it helps in combating stretch marks and cellulite. It is an ideal solution for individuals with more advanced dermatological issues. With needle mesotherapy, the skin becomes firmer and radiates with health.

When is it worth choosing microneedle mesotherapy?

Microneedling mesotherapy is a great option for those who want to improve the elasticity and blood circulation of their skin. This treatment removes minor imperfections, giving the skin a healthy glow. Thanks to the micro-punctures, the skin becomes better moisturized and firmer, contributing to a younger appearance. This method is ideal for people who want to improve the condition of their skin without interfering with its deeper layers.

It is worth mentioning that microneedling mesotherapy is less invasive than traditional needle mesotherapy. For this reason, it is often chosen by people who want to avoid pain or a long recovery period after the treatment. An additional benefit of this technique is the possibility of even stimulation through manual or automatic devices, which affects the precision and comfort of the treatment. For those who want to refresh their skin without deep interference, microneedling mesotherapy is an excellent solution.

How does the procedure of needle mesotherapy proceed?

Mesotherapy involves introducing nourishing substances directly into the skin using a thin needle. The process begins with cleansing and disinfecting the skin, followed by applying a numbing cream to alleviate discomfort. After about half an hour, the doctor performs a series of injections, delivering active ingredients to a depth of 1 to 4 mm, depending on the specific area of the body.

The procedure typically lasts from half an hour to an hour and is carried out smoothly thanks to the use of delicate tools. After completion, the skin is protected with a UV filter cream, allowing it to be shielded from sunlight and aiding in its regeneration.

How does the procedure of microneedling mesotherapy look like?

Microneedle mesotherapy begins with careful skin cleansing. Then, a numbing cream is applied to minimize any potential discomfort. After about half an hour, the skin is ready for the next stage of the procedure, during which a specialized product with active ingredients such as hyaluronic acid, vitamins, and peptides is applied. The microneedle mesotherapy device makes hundreds of micro-punctures at depths ranging from 0.5 to 2.5 mm, stimulating the skin's regenerative processes and promoting the production of collagen and elastin. The entire procedure typically lasts about an hour. There is no need for a long recovery period after the treatment. Following microneedle mesotherapy, it is recommended to use sunscreen creams and avoid sun exposure to protect the delicate skin from harmful UV rays.

What are the contraindications for needle mesotherapy and microneedling?

Contraindications for needle and microneedle mesotherapy include several important health issues. These procedures are not recommended for:

  • Pregnant and breastfeeding women
  • Individuals with viral, bacterial, or fungal infections,
  • Patients with cancerous diseases,
  • During isotretinoin therapy,
  • Individuals with allergies to the components used during the treatments,
  • People suffering from diabetes.

Patients with cancerous diseases should refrain from the procedures due to the risk of stimulating cancer cells. Additionally, isotretinoin therapy eliminates the possibility of undergoing mesotherapy due to its effects on the skin. Individuals with diabetes must exercise special caution when considering mesotherapy due to their wound healing issues. Before deciding on mesotherapy, it is always advisable to consult a specialist doctor to discuss contraindications to the procedure and assess potential risks.

How to take care of the skin after microneedling and mesotherapy treatments?

After treatments such as mesotherapy with needles or microneedling, it is crucial to take proper care of the skin so that it can effectively regenerate.

  • For the first 24 hours after the procedure, avoid anything that may irritate the skin (e.g. sauna, swimming pool, intense physical activity).
  • Limit skin exposure to UV rays.
  • Maintain body hygiene.
  • Avoid using cosmetics containing irritating chemicals – opt for a mild cleansing gel and special creams that support skin regeneration.
  • Refrain from consuming alcohol, as it may have a negative impact on the body's regenerative processes.

Adhering to these guidelines significantly improves the effects of mesotherapy and accelerates skin regeneration.