Karisma or Profhilo?

14.11.2025
Karisma and Profhilo are two groundbreaking aesthetic treatments that effectively restore a youthful appearance to the skin, although they work in different ways. Karisma, known as a 'soft filler,' stimulates collagen production, providing firmness and revitalization to the skin. On the other hand, Profhilo sculpts and deeply hydrates the skin, counteracting its sagging. Discover how these innovative treatments can impact your skin and what results you can expect from them.
What is Karisma biostimulator, and what is Profhilo?

Karisma is an innovative tissue biostimulator, often referred to as a "soft filler." Its main task is to stimulate the natural production of collagen, effectively rejuvenating the skin. This preparation provides a number of benefits:

  • significantly improves skin firmness,
  • increases skin elasticity,
  • revitalizes the complexion,
  • subtly, naturally fills wrinkles,
  • effectively rejuvenates the skin.

On the other hand, Profhilo is a unique preparation for skin bioremodeling, known as the "youth molecule." Its action consists of deep skin moisturization. Profhilo brings the following effects:

  • effectively counteracts skin laxity,
  • restores a youthful appearance to the face,
  • activates natural repair processes in tissues,
  • activates natural regenerative processes in tissues,
  • deeply moisturizes the skin.

Although both biostimulators are highly popular and rejuvenate the skin, their mechanisms of action differ significantly.

What are the main differences in composition and mechanism of action?

The key difference between the treatments lies in their ingredients and mode of action. **Karisma** stands out for its unique Rh collagen, obtained from silk threads using NEOSILK technology. It also contains hyaluronic acid and CMC (carboxymethylcellulose). The preparation works by actively stimulating the skin to produce new, natural collagen. Additionally, CMC acts as a potent antioxidant, protecting the skin's natural hyaluronic acid.

Profhilo is based solely on pure, stabilized hyaluronic acid, which comes in two forms with different molecular weights. The lighter fraction intensely moisturizes the skin and stimulates collagen and elastin production. The heavier fraction creates internal "scaffolding" and provides a lifting effect. In contrast to Karisma Profhilo does not utilize collagen.

What effects can be expected after both treatments?

Karisma naturally rejuvenates the skin, significantly improving its condition. This treatment makes the skin firmer, more elastic, denser, deeply moisturized, and regenerated. Fine lines are smoothed out, and scars and stretch marks are reduced. The complexion gains a fresh, radiant look.

Profhilo works differently, providing a stronger lifting effect. The treatment:

  • neutralizes skin sagging, particularly visible in the lower parts of the face,
  • improves facial contour and oval shape,
  • visually slims the features,
  • intensely moisturizes the skin,
  • restores lost skin elasticity.

Both treatments, although they differ in their mechanism of action, support the skin's health, giving it a radiant appearance.

Who is the Karisma procedure intended for, and who is Profhilo intended for?

Karisma is the perfect solution for individuals over 25 years old who notice the first signs of aging. It effectively counteracts skin sagging, smooths fine lines, significantly improves overall skin condition, and helps reduce acne scars.

Profhilo is primarily designed for mature skin, usually over 35 or 40 years old. It works well on visible signs of aging, helps restore the proper oval shape of the face, eliminates "hamster cheeks," and provides intense lifting, particularly noticeable in the lower parts of the face.

Importantly, both treatments can also be successfully applied on the neck, décolletage, and hands.

What is the surgical procedure and recovery period like?

The Karisma and Profhilo treatments are minimally invasive procedures that require precise injections. To ensure maximum patient comfort, occlusive anesthesia is used.

Karisma product is applied using a retrograde linear technique, with a needle or cannula. A typical treatment cycle consists of two sessions, performed one month apart. Regular maintenance sessions are recommended to maintain long-lasting results.

On the other hand, Profhilo is administered using the innovative BAP (Beauty Aesthetic Points) technique. This method involves making only five precise injections on each side of the face, significantly minimizing discomfort and the risk of bruising. A series of two sessions is recommended, with a break of approximately 30 days between them.

The recovery period after both procedures is usually very short. It is worth noting that after the Profhilo treatment, small, palpable lumps may sometimes appear - these are deposits of the product that will be absorbed spontaneously, typically within just a few hours.

What are the contraindications for procedures and possible side effects after their performance?

Karisma and Profhilo are extremely safe treatments, with ingredients that are biocompatible and easily assimilated by the body. Importantly, the Karisma preparation does not trigger allergic reactions.

However, certain contraindications for the treatments should be kept in mind. These include:

  • pregnancy,
  • breastfeeding,
  • active cancer,
  • autoimmune diseases,
  • skin infections,
  • confirmed allergy to any of the ingredients.

Potential side effects of the preparations are usually mild and short-lived. They may include slight redness, mild swelling, tenderness at the injection site, or minor bruising that rapidly fades.

If the aesthetic result after a procedure using hyaluronic acid (e.g., Profhilo, Karisma) is unsatisfactory, hyaluronidase can be used – an enzyme that effectively dissolves the preparation.

Karisma or Profhilo - which one to choose for skin problems?

The choice of the right cosmetic product depends on the specific skin issue and expected results. If you aim to improve skin condition and density, Karisma will be an excellent choice. It effectively reduces fine lines, scars, or stretch marks, acting both preventively and correctively. It ensures natural skin rejuvenation and subtle filling of wrinkles. Its action includes:

  • improvement of skin condition,
  • reduction of fine lines,
  • reduction of scars,
  • reduction of stretch marks,
  • natural skin rejuvenation,
  • subtle filling of wrinkles.

On the other hand, Profhilo is perfect for advanced skin sagging, especially when the oval of the face starts to drop. This product provides:

  • strong facelift,
  • noticeable improvement in skin tension,
  • formation of internal skin scaffolding,
  • reduction of skin sagging,
  • support for the dropping face oval.

Often, the best results come from combined therapy. Specialists recommend using both products on different skin areas, as well as combining them with other advanced technologies such as:

  • laser,
  • HIFU,
  • radiofrequency,
  • botox,
  • chemical peels.